IV Vitamin C has been widely used in complementary medicine to treat cancer patients with good results and now a new study published in Science corroborates this hypothesis.
Since the 1970s, ascorbic acid has been used as adjunctive therapy for the treatment of cancer, mainly supported by its few side effects. In addition, it was used in routine clinical oncology practice but it was abandoned due to multiple clinical trials showed it as ineffective. However, in all cases, it was administered orally.
In 2006, Dr. Padayatty presented three cases of terminal cancer patients given up by Western medicine who recovered and survived after intensive treatment with vitamin C intravenously.
The doses used in natural medicine vary from 7.5 to 30 g per day to 100 g, and this for weeks or months, depending on the evolution of cancer. These megadoses of vitamin C have been shown to have fewer side effects and have contraindications listed below.
It appears that its mechanism of action is the formation of hydrogen peroxide (oxygenated water) in the interstitial tumor tissue, which can destroy many tumor cells, but the peroxide is not formed in the blood and thus, side effects are avoided in the rest of the body. Another possible mechanism of action is the immune modulation of tumor cells, leading thereof, to apoptosis (suicide). Tumors which development has shown decrease include prostate, pancreatic, colon, leukemia, melanoma, and breast cancer among others.
Oral supplements have not demonstrated improved survival in cancer patients nor be useful for the prevention of this disease.
When vitamin C is administered intravenously, the blood concentrations acquire ten times higher than orally, and at these doses is when vitamin C exerts its anticancer effect. We would have to take enormous amounts of food or supplements to achieve the effective dose.
The intake between 75 and 100 mg of vitamin C a day is recommended to prevent cancer but is not useful to treat it. That is, to prevent it, we would have to take two oranges a day, or a guava, or raw red pepper, a handful of strawberries, two kiwis, or papaya. But this dose would not be adequate for anti-tumoral purposes.
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H.D Riordan et al. Intravenous ascorbic acid: Protocol for ITS application and use. Vol.22 PRHSJ n3, september 2003.
Park S et al. L-ascorbic acid Induc apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediate Mechanisms. The International Journal of Biochemistry and Cell Biology. 36 (2004), 2180-2195.
Padayatty S. et al. Vitamin C: intravenous use by alterbative and complementary medicine practitioners and Adverse effects. PLoS ONE 5 (seventh): e11414.doi: 10.1371 / journal.pone. 0011414.
Duconge J. et al. Pharmacokinetics of vitamin C: insights into the oral and intravenous administration of ascorbate. PRHSJ Vol.27 No.1. March, 2008.